Several endocrine diseases are linked to abnormal ACTH levels. The most common ones include Cushing’s disease (too much ACTH) and Addison’s disease (too little cortisol, causing excess ACTH).

Associated Disorders

• Cushing’s disease: Excess ACTH - high cortisol.
• Addison’s disease: Adrenal failure - high ACTH.‍
• Secondary adrenal insufficiency: Pituitary issue - low ACTH.